In the exploration of modernized extraction process of Chinese herbal medicines, Pueraria lobata, as a medicinal plant rich in isoflavonoid active ingredients, the isolation and purification of its active ingredients have been the focus of the industry. In the traditional extraction process, the target components such as Pueraria lobata and soybean glycosides often face the problems of low extraction efficiency, high impurity residues and high energy consumption. In recent years, the introduction of ceramic membrane filtration technology has brought breakthroughs in this field, and its advantages in polymer retention, thermal stability and anti-pollution are reshaping the production process and quality standards of Pueraria lobata extraction.
The core value of ceramic membrane filtration technology in Pueraria lobata extraction is embodied in the accurate screening of complex systems. In the aqueous or alcoholic extract of Pueraria Lobata, in addition to the target active ingredients, often mixed with colloids, proteins, tannins and other macromolecular impurities. The traditional process of centrifugation, plate and frame filtration or resin adsorption is not only cumbersome, but also may result in the loss of components due to high temperature or the introduction of chemical reagents. Ceramic membranes, with their uniform nanometer-sized pore size, can directly intercept macromolecular impurities at room temperature, while allowing small molecules of active substances to pass through freely. This physical screening mechanism not only avoids degradation of heat-sensitive components, but also significantly shortens the subsequent concentration and refining cycle.
More importantly, the application of ceramic membrane filtration technology promotes the green transformation of Pueraria lobata extraction process. Compared with the traditional method of frequent use of organic solvents or acid and alkali treatment, ceramic membrane filtration operates in a purely physical way, significantly reducing the chemical oxygen demand (COD) and biological toxicity of wastewater discharge. This feature is highly compatible with the current requirements of cleaner production in the traditional Chinese medicine industry. In addition, the regeneration performance of the ceramic membrane significantly reduces the long-term operating costs - through the reverse flushing and chemical cleaning, its flux recovery rate of up to 90% or more, the service life of more than 5 years, which allows small and medium-sized pharmaceutical companies can also be a low threshold to realize the technological upgrading.
More importantly, the application of ceramic membrane filtration technology promotes the green transformation of Pueraria lobata extraction process. Compared with the traditional method of frequent use of organic solvents or acid and alkali treatment, ceramic membrane filtration operates in a purely physical way, significantly reducing the chemical oxygen demand (COD) and biological toxicity of wastewater discharge. This feature is highly compatible with the current requirements of cleaner production in the traditional Chinese medicine industry. In addition, the regeneration performance of the ceramic membrane significantly reduces the long-term operating costs - through the reverse flushing and chemical cleaning, its flux recovery rate of up to 90% or more, the service life of more than 5 years, which allows small and medium-sized pharmaceutical companies can also be a low threshold to realize the technological upgrading.
Ceramic membrane technology is accelerating the high-value development of Pueraria lobata extract. By regulating membrane pore size and operating parameters, companies can flexibly adjust the molecular weight distribution of target products to suit the needs of different end products. For example, for high purity pueraria lobata needed for cardiovascular drugs, nanofiltration membranes with smaller MWCOs can be used for gradient separation; while for functional foods, some polysaccharides can be retained to enhance synergistic effects of the product.
In the future, with the breakthrough of ceramic membrane material modification technology (e.g. hydrophilic coating, anti-protein adsorption surface treatment), the boundary of its application in Pueraria lobata extraction will be further expanded. From single-component purification to multi-component synergistic retention, from laboratory-scale validation to 10,000-ton industrialization landing, this technology is writing a new chapter in the extraction process of traditional Chinese medicine - not only to retain the natural attributes of traditional medicinal herbs, but also endowed with the sophisticated qualities of modern industry.
Here is the Holves brand website, https://www.bjholves.com/. Providing different types of industry information, technical knowledge, and solutions, we have developed and produced several new laboratory fermenter, bioreactor, tangential flow filtration system and other equipment to meet your needs from experimental to industrial production.
In the future, with the breakthrough of ceramic membrane material modification technology (e.g. hydrophilic coating, anti-protein adsorption surface treatment), the boundary of its application in Pueraria lobata extraction will be further expanded. From single-component purification to multi-component synergistic retention, from laboratory-scale validation to 10,000-ton industrialization landing, this technology is writing a new chapter in the extraction process of traditional Chinese medicine - not only to retain the natural attributes of traditional medicinal herbs, but also endowed with the sophisticated qualities of modern industry.
Here is the Holves brand website, https://www.bjholves.com/. Providing different types of industry information, technical knowledge, and solutions, we have developed and produced several new laboratory fermenter, bioreactor, tangential flow filtration system and other equipment to meet your needs from experimental to industrial production.
