Bio Intelligent Pump
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The newly developed K₂P Series intelligent pump from HOLVES uses a Quattroflow® four‑piston diaphragm pump as its core power source, maintaining low shear and low pulsation performance. This series is equipped with built‑in K₂P‑Control filtration software, eliminating the need for cumbersome external installation and setup, thus greatly simplifying experimental and production processes and improving work efficiency.
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HOLVES has been focusing on creating high-quality fluid solutions for users in the field of biopharmaceuticals and providing comprehensive and high-quality product support services to meet the industry's development needs.
Soft Delivery, Low Pulse, Low Shear
The diaphragm pump operates similarly to the mammalian heart: through the coordinated action of the diaphragm and inlet/outlet check valves, it alternates between suction and discharge cycles, continuously generating flow and pressure. The core power system of this series – the four‑piston diaphragm pump – is supplied by German Quattroflow and employs its unique four‑piston technology, which mimics the beating of the human heart to achieve safe and reliable transfer of biological materials. The pump body uses elastomeric check valves and diaphragms, with smooth, rounded flow channels designed to minimise sharp edges inside the fluid path, thereby reducing shear stress to the lowest possible level. Furthermore, there are no mechanical seals or wetted rotating parts inside the pump, ensuring complete sealing and eliminating wear, which significantly reduces particle generation. Quattroflow pumps exhibit low friction, low shear, and low pulsation, allowing gentle, safe, and stable pumping of shear‑sensitive aqueous solutions and biological products, with minimal impact on the product.
- Core power system: Quattroflow® four‑piston diaphragm pump – mimics heart operation, low shear, low pulsation
- Adopts elastic check valves and diaphragms, designed with smooth rounded flow channels to minimize sharp shapes.
- There are no parts in the pump that are prone to wear and heat generation, safer and more stable.
- The diaphragm pump can deliver softly ,minimizing the impact on the product.
Sanitary Design, Safe and Efficient
The unique flow channel structure ensures that the pump head, especially the diaphragm chamber, can be completely emptied of liquid at the end of the work without any accumulation of liquid. The metal parts are made of SS316L stainless steel, and the surfaces in contact with liquid are machine polished and electropolished so that the surface roughness is Ra<0.4um, and meets the standard requirements of ASME BPE. All non-metallic bodies in contact with liquids (diaphragms, check valves, seals, etc.) are made of FDA and USP Class VI compliant materials to ensure material safety and to meet the stringent pharmaceutical grade requirements.
The meticulous design gives the product a lively life
- Pump body: Quattroflow® four‑piston diaphragm pump, with no mechanical seals or wetted rotating parts, ensuring complete sealing integrity;
- High-grade matte surface of the shell, snap-on design, simple and aesthetic;
- The rich electrical interfaces support plug-and-play functionality,easily manage various traffic tasks；
- 4.3 / 7 inch HMI color touch screen, more intuitive function parameters, experimental operation, to enhance the user's sense of use.
Intelligent operating system, from complexity to simplicity
- The product is built-in with the new generation K₂P-Control software system, which brings industrial-grade human-machine interaction experience;
- By configuring accessories such as pressure sensors and flow meters, it is possible to realize constant current and constant pressure;
- Dispensing function for delivering fluids at regular time and quantity;
- With data recording, curve analysis, alarm setting, audit trail and many other function modules.
K₂P-Serics Intelligent Pump
| Mode | K₂P-60 | K₂P-180 | K₂P-1200 | K₂P-2500 | K₂P-5500 |
| Flow rate (L/H) | 60 | 180 | 1200 | 2500 | 5500 |
| Flow rate accuracy | ±2% | ±2% | ±2% | ±2% | ±2% |
| Maximum pressure resistance | Medium temperature ≤40℃: 6bar; Medium temperature ＞40℃: 4bar | ||||
| Connection size | 1/4”TC | 1/4”TC / 1/2”TC | 3/4”TC | 1”TC | 1.5”TC |
| CIP/SIP | 0.1-1M NaOH，121℃ SIP | ||||
| Pump configuration | Quattroflow® pump standard – pump chamber: SS316L, diaphragm: TPE, seals: EPDM | ||||
| Shell material | Matte stainless steel no fingerprints process | ||||
| Software version | K₂P-Control V1.0 | ||||
| Power (KW) | 0.2 | 0.2 | 0.9 | 2.0 | 4.0 |
Application
TFF
Deep filtration
De-virus filtration
Chromatography
Liquid dispensing
Replenishment
Perfusion culture
Fluid delivery
Product Brochure
The newly developed K₂P series of intelligent pumps from HOLVES uses Quattroflow® four-piston diaphragm pump as the power system, which has the characteristics of low shear and low pulsation. This series of intelligent pumps can greatly simplify the experimental and production process and improve work efficiency.
